A spider is an arachnid, which has eight legs. A spider is typically carnivorous, eating insects or other small animals.
A drider, originally, was a monster from Dungeons and Dragons - a dark elf cursed with the lower body of a huge spider, similar to a centaur form. However, like taurs, a drider form can be generalised to any human or anthro form.
The people of West Africa have a mythical hero called Kwaku Anansi, or First Spider. Anansi is a trickster, often noble and wise, who did things like bringing stories from Heaven to Earth. He also did things like hiding hot beans under his hat when his friends were hungry, thus forever burning his hair away.
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 See also
- Spider on Wikipedia