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In the comic Freefall, the fictional Bowman's Wolf is a species of transgenetically engineered Red Wolf (Canis rufus), whose genes were sequenced by EcoSystems Unlimited as a proof-of-concept test to judge the feasability of producing a series of fully sentient beings of creatures native to a planet named Pfouts. Pfouts' life uses right handed amino acids, making the planet incompatible with Earth life forms. Artificially uplifted Pfoutsian creatures would share Earth's culture (lacking one of their own), as well as being able to take advantage of their world's resources (and potentially trade) with which would otherwise not be accessible as full-scale terraforming is prohibitively expensive.
Under the direction of Dr. Bowman, 14 "Generation Zero" prototype wolves came to full term (3 males, 11 females.) After project "Pfouts" was canceled, "a series of clerical errors resulted in the inadvertent release of the Bowman's Wolf to the general public," resulting in all pups being placed in the care of compatible human families before EcoSystems Unlimited could begin their specimen sterilization and disposal program.
Dr. Bowman and his now-adult wolves are currently engaged in a social, ethical, and legal battle with EcoSystems Unlimited; the goal is to appeal to the company's greed while also proving the inherent technological viability of restarting the "Bowman's Wolf" project.
 Miscellaneous notes
From a business perspective, "Bowman's Wolves" have demonstrated themselves to be a perfect "proof of concept" experiment, in that they are totally dependable, highly adaptable to social interaction, and have enough "Human Safe" fail safes built into them to give most critics pause. Since their diet and biology are quite similar to that of dogs, medical and food infrastructure (which for a more divergent species would be sorely lacking at best) are already in place on most worlds, so their cost-of-maintenance is quite manageable. (Besides, veterinarians often cost less than human doctors.)
The work and help they could provide in their expected life span of 160 years could cover (in theory) any economic risk inherent in owning one. The only caveat is that, for all purposes, they are still considered "free thinking/free will" property, much like sentient robots, with the additional distinction that all their derivative products (e.g., "pups") remaining the private property of EcoSystems Unlimited.
 Bowman's Wolves in furry media
- Name: Ambrose, Florence
- Sex: Female Bowman's Wolf
- Earth age: 26
- Place of birth: ???, Earth
- Genetic "Parents": Red Wolf, some bear DNA
- Gestation parent: Earth female St. Bernard Dog.
- Owner: Scott Ambrose, son of an Italian woman and a Thai man.
- Present assignment: Senior ship's Technical Engineer onboard the "Savage Chicken," registry number 1071-CCN, Captain Starfall, Sam, commanding.
- Primary weapons: Screwdriver, Toothy smile.
- Back-up weapon: Duct tape (and lots of it)